The 2025 World Reputation Ranking, published on February 18, 2025 by Times Higher Education (THE), places Sapienza in 90th position, moving up from the 91-100 range of the 2024 ranking. Sapienza is also top Italian university, followed by the University of Bologna in 92nd place and the Politecnico di Milano in the 101-150 range.

The Times Higher Education's World Reputation Ranking lists the world's top 300 universities and is based on an extensive, invitation-only survey of academics. The survey asks academics from a range of disciplines to nominate up to 15 institutions for research and up to 15 institutions for teaching. They are also asked to rank five universities, the names of which are given to each respondent based on their research experience. The latest edition of the survey received 55,000 responses.

This result", says Rector Antonella Polimeni, "gives me particular pleasure because it comes on the eve of the opening of Sapienza academic year, which will be celebrated for the first time on the Rieti campus. Sapienza's excellent performance in the ranking, among the top 100 in the world, confirms the prestige that Sapienza enjoys internationally thanks to the quality of its teaching and research, which the University also intends to promote and test locally'.

Leading the global ranking are Harvard University, Massachusetts Institute of Technology and University of Oxford.