Experimental and clinical Hepato-gastroenterology

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Criteri di valutazione

CRITERI DI VALUTAZIONE - 34° CICLO Nella assegnazione dei punteggi la Commissione potrà valutare singolarmente i seguenti criteri ed attribuire un punteggio complessivo che sia espressione della sommatoria delle singole valutazioni. Prova scritta  Conoscenza e competenza della tematica oggetto della prova  Capacità di sintesi e chiarezza nell'elaborazione della prova  Completezza descrittiva e recenti acquisizioni del tema oggetto della prova Per il superamento della prova il candidato deve ottenere un punteggio di almeno 40/60. Prova orale  Discussione sulle tematiche dei rispettivi curricula del Dottorato  Chiarezza espositiva, capacità di sintesi e terminologia scientifica appropriata  Lingua inglese Per il superamento della prova il candidato deve ottenere un punteggio di almeno 40/60. Il punteggio minimo complessivo deve essere di almeno 80/120. SCORING CRITERIA – 34rd CYCLE In marking the candidates, the Commission will evaluate the following criteria individually and give a total score which comes from the sum of the individual assessments. Written Test  Knowledge and competence on the topic of the test  Capacity of synthesis and clarity in carrying out the test  Comprehensive description and updated knowledge regarding the subject of the test To pass the test, the candidate must achieve a score of at least 40/60 Oral Test  Debate about the topics of the specific PhD curricula  Clear presentation, ability to summarize and appropriate use of the scientific terminology  English language To pass the test, the candidate must achieve a score of at least 40/60. The minimum total score must reach at least 80/120

Educational goals

The main objective of the PhD Program "Experimental and clinical hepato-gastroenterology" is to provide the basis to train researchers capable of performing, independently, experimental and clinical researches in the hepato-gastroenterological field. This objective will be obtained by offering PhD students theoretical, experimental and clinical training courses. These courses allow to learn the most updated laboratory methods and the application of the experimental methodologies in research projects. The main aim is solving etiopathogenetic, diagnostic and therapeutic problems in hepato-gastroenterology. The PhD course offers an interdisciplinary project-oriented postgraduate education for medical students as well as for students from life sciences. While working on a 3-year research project, students learn how to carry out an independent scientific work and also learn further skills or abilities in research and teaching. They acquire basics and methods in Medicine and Biology and their application on current research projects in the morphological/ultrastructural, molecular and clinical aspects of the digestive system in human and experimental models. The project clinical oriented on digestive illness, tumors and transplants will be developed in Experimental and clinical hepatology curriculum, while the project surgical oriented will be developed in Surgical pathophysiology and gastroenterology curriculum. The scientific research projects are carried out in one of the Departments associated to the PhD Program allowing the integration between basic and clinical sciences. The ongoing interaction between students and academic advisory board in which are included experts in the anatomy, biology and clinical and surgical gastroenterology sciences, provides the scientific validity of the projects. The solid interaction between Clinical Departments and Basic Science Laboratories gives a specific clinical characterization to the study projects. Numerous co-operations with outstanding scientists and institutes guarantee the scientific excellence of the program. Short-term stages in other Italian or international institutions within the scope of co-operations and projects are highly desired. The University Institutions involved in the fellowship program are: Liver Unit, Yale University, New Haven, CT, USA; Texas A&M University, Temple, Texas, USA; Unité “T. Starzl” de Transplantation abdominale, Université Catholique de Leuven, Belgio; Liver Unit, Hospital Clinic of Barcelona, Spain; Western University of Birmingham, UK; General Hospital, Edinburgh University, UK; North Carolina University, UNC School of Medicine, Chapel Hill, NC, USA. Colleagues from these or other qualified research/clinical/surgical centers will act as advisors external consultants. The PhD Program is mainly aimed to the acquisition of an interdisciplinary research approach. During the 3-year period of the PhD Program students will use advanced experimental methodologies of morphology, molecular and cellular biology in an attempt to resolve clinical and surgical hepato-gastroenterological issues. Main Program Learning Objectives - Up-to-date knowledge in the cellular and molecular basis of development and progression of hepatic, pancreatic, and gastrointestinal tract diseases. Interest is mainly focused on the mechanisms determining cellular damage (necrosis and apoptosis), tissue repair (regeneration and cellular proliferation, fibrosis), and microvascular features. - Identification and use of bio-molecular, histo-morphological, histo-chemical, immune-histochemical and ultrastructural tools to analyze key aspects of the gastrointestinal tract, hepatic damages and the pathophysiology of the splanchnic microvascular circle. - Planning and developing study projects aimed to identifying the mechanisms regulating the gastrointestinal tract, hepato-pancreatic, biliary and endothelial cells death and proliferation in order to evaluate therapeutic strategies in the treatment of digestive system chronic diseases. - Planning and developing study projects aimed to identifying histological, immune- histochemical and molecular markers in neoplastic and non-neoplastic gastrointestinal tract, liver and pancreas, diseases useful in predicting disease progression and/or response to therapy. - Planning and developing study projects aimed to preparing both differentiated and undifferentiated liver cultured cells suitable in human and in experimental models transplantation. - Planning and developing study projects aimed to elaborating the knowledge of pathophysiology illness of the digestive system with special consideration to digestive neoplasia, following surgical procedures and/or after organ transplants. - Planning and developing study projects aimed to the knowledge of molecular genetics, immune and neuroendocrine mechanisms of endocrine diseases in order to evaluate new therapeutic strategies and to develop innovative surgical methods (e.g. minimally invasive surgery, radio-immuno-guided surgery, etc.).

Exam - written

Giorno: 9/7/2018 Ora: 09:00 Aula: Aula B Primo Piano di Anatomia Indirizzo: Via Alfonso Borelli 50 00161 Roma

Exam - Oral

Giorno: 24/7/2018 Ora: 09:00 Aula: Aula B Primo Piano di Anatomia Indirizzo: Via Alfonso Borelli 50 00161 Roma


Membri effettivi

Prof.ssa Annamaria Pronio - Sapienza Università di Roma
Prof. Antonio Franchitto - Sapienza Università di Roma
Prof. Domenico Alvaro - Sapienza Università di Roma
Prof. Paolo Negro - Sapienza Università di Roma
Prof. Stefano Ginanni Corradini - Sapienza Università di Roma

Membri supplenti

Prof. Francesco Angelico - Sapienza Università di Roma
Prof. Oliviero Riggio - Sapienza Università di Roma
Prof. Paolo Onori - Sapienza Università di Roma 



Scienze anatomiche, istologiche, medico-legali e dell'apparato locomotore
Phone contacts

+39 28062 - 28075


Paolo Onori

Scienze mediche, sperimentali e cliniche

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