In the next decades, nations will face issues related to energy and environment to ensure an actually sustainable development, combining the available resources with the respect for nature. Interdisciplinary, transnational and innovative knowledge and skills play a crucial role, as they allow facing complex issues involving not only technological features, but also social, economic and environmental aspects. The PhD Course in Energy and Environment provides multidisciplinary skills and knowledge, highly integrated, in order to form professional figures able to operate in the worlds of research, business, government institutions, both national and international, as well as cooperation. These figures can deal, with an adequate cultural base, the challenge of energy development, in harmony with the environment and man, in an international context including the industrialized, emerging and developing countries. This objective is achieved through four cultural addresses: the first in "Machinery and Systems for the Energy and the Environment", the second in "Industrial and Environmental Technical Physics", the third in "Nuclear Engineering", the fourth in "Energy Saving and Distributed Micro-Generation". These four addresses, while differing in some specific contents, share a common base of knowledge and, above all, methodological approach ensuring a strong correlation among the different cultural fields represented by energy sciences, environment protection and development policies. The PhD Course in Energy and Environment, which lasts three years, is organized in such a way that every student can take advantage of all the skills available within the four cultural addresses. The educational structure of the PhD course consists of a first phase, common to all the cultural addresses, in which the fundamentals of research will be treated, and in two subsequent phases, respectively aimed at deepening the topics typical of any cultural address and preparing the PhD thesis.